MEGA: Primary prevention of cardiovascular disease with pravastatin in Japan
principal researchers
Haruo Nakamura (Mitsukoshi Health and Welfare Foundation, Tokyo)
data custodian
MEGA Study Group
funding
Japanese Ministry of Health, Labor and Welfare for the first 2 years of the study; thereafter by Sankyo Co Ltd, Tokyo
key publications
- Design paper: Circ J 2004; 68: 860–867
- Main results: Lancet 2006; 368: 1155–63
- Effects on cancer: Lipids Health Dis 2014; 13: 133
- Effects in women: Circulation 2008; 117(4): 494-502