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news

2026

CTT publication in The Lancet: Assessment of adverse effects attributed to statin therapy in product labels: a meta-analysis of double-blind randomised controlled trials

 

2024

CTT publication in The Lancet Trials and Endocrinology: Statins can cause a small increase in blood sugar levels, so people at high risk may develop diabetes sooner

 

2022

CTT publication in The Lancet: New study shows muscle pain is not due to statins in over 90% of those taking the treatment

CTT publication in Clinical Trials: Methodology paper

2019

CTT publication in The Lancet: Statin therapy reduces cardiovascular disease risk in older people

2016

ASCOT-LLA publishes adverse event analyses

The Lancet publishes major review about the use of statins citing evidence from CTT

CTT publication in The Lancet Diabetes and Endocrinology: Impact of renal function on the effects of LDL-cholesterol lowering with statin-based regimens

CTT publication in The American Heart Journal: adverse event protocol

Tabular data (all Serious Adverse Events by MedDRA classification) now available for HPS and SEARCH trials

2015

CTT publication in The Lancet: statin treatment reduces the risk of cardiovascular disease in women

2010

CTT publication in The Lancet: more intensive statin treatment leads to greater reductions in the risk of major cardiovascular events than regular doses

2005

CTT publication in The Lancet: specific benefits of statins identified