PROSPER: PROspective Study of Pravastatin in the Elderly at Risk
principal researchers
Ian Ford (University of Glasgow)
J Wouter Jukema (Leiden University)
Naveed Sattar (University of Glasgow)
data custodian
University of Glasgow
funding
Bristol-Myers Squibb
key publications
- Design paper: Am J Cardiol 1999; 84:1192-1197
- Baseline characteristics: Curr Control Trials Cardiovasc Med 2002; 3(1): 8
- Main results: Lancet 2002; 360: 1623–30
- Cost-effectiveness in the elderly: Control Clin Trials 2002; 23(6): 757-773
- Cognitive function in elderly populations: J Neurol Neurosurg Psychiat 2002; 73: 385-9
- Predictors of functional decline in elderly people: Age Ageing 2005; 34(5): 450-5
- Plasma lipoproteins as predictors of risk: Circulation 2005; 112(20): 3058-65
- Cerebral infarcts and white matter lesions: Neurology 2005; 64: 1807-9
- C-reactive protein: Circulation 2007; 115: 981-9
- Apolipoprotein E-4: J Am Geriatr Soc 2007; 55(11): 1777-85
- Effect of genetic variation at the PCSK9 locus: Atherosclerosis 2008; 200: 95-101
- HMG-CoA reductase gene loci: Atherosclerosis 2008; 200: 109-14
- Psychological, social & biological determinants of ill health: BMC Public Health 2008; 8: 126
- Interleukin–Iβ-converting enzyme: Brain 2008; 131: 1069-77
- Lymphotoxin-alpha C804A polymorphism: Exp Gerontol 2008; 43: 801-5
- Alcohol Intake: J Am Geriatr Soc 2008; 56: 2217-24
- Metabolic syndrome and diabetes: Lancet 2008; 371(9628): 1927-35
- Apolipoprotein E Genotype: Am J Epidemiol 2009; 170(11): 1415-21
- Proinflammatory Cytokines: Clin Can Res 2009: 15(24): 7744-8
- Leptin: Diabetes Care 2009; 32(2): 308-10
- Intercellular adhesion molecule 1 levels: Diabetologia 2009; 52(2): 235-9
- Adipocytokines and risk of stroke: Int J Epidemiol 2009; 38(1): 253-61
- Glomerular Filtration Rate: PLoS Medicine 2009; 6(1): 76-82
- Markers of inflammation: PLoS Medicine 2009; 6 (6): e1000099
- Effects on cognitive function: J Neurol 2010; 257(1): 85-90
- Cognitive Function: Arterioscler Thromb Vasc Biol 2010; 30(3); 605-11
- Inflammatory biomarkers: Atherosclerosis 2010; 210(1): 28-34
- KIF6 Trp719Arg polymorphism: Eur J Cardiovasc Prev Rehabil 2010; 17(4): 455-61
- Cholesterol absorption and synthesis markers: J Lipid Res: 2010; 51: 202-9
- Adiposity and inflammation: J Clin Endocrinol Metab 2010; 95(1): 93-9
- NPC1L1 gene locus: J Lipid Res 2010; 51(5); 1201-1207
- Interleukin-10: Arterioscl Throm Vas 2011; 31(10): 2338-44
- New onset atrial fibrillation: Europace 2011; 13(5): 634-9
- SLCO1B1 gene locus: Atherosclerosis 2012; 220(2): 413-7
- KIF6, LPA, TAS2R50, and VAMP8 genetic variation: Atherosclerosis 2012; 220(2): 456-62
- Subclinical Thyroid Dysfunction and heart failure: J Clin Endocrinol Metab 2012; 97(3): 852-61
- Galectin-3 gene and cognitive function: Neurobiol Aging 2012; 33(9): 2232 e1-2232 e9
- Blood Pressure Variability and Cardiovascular Risk: PLOS One 2012; 7(12): e52438
- Prospective cohort study: BMJ Open 2013; 347: f4600
- Interleukin-6 concentration and cognitive decline: J Intern Med 2013; 274 (1): 77-85
- PCSK9 SNP rs11591147: J Lipid Res 2013; 54 (2): 561-6
- Total cerebral blood flow - 12-yr follow-up: Neurology 2013; 81 (22): 1922-1929
- 3.2 year follow-up: PLoS One 2013; 8(9): e72642
- N-Terminal Pro-Brain Natriuretic Peptide: Ann Neurol 2014; 76(2): 213-22
- ABCA1 gene variation: Atherosclerosis 2014; 235(1): 176-81
- Pharmacogenetic study: Atherosclerosis 2014; 235(1): 58-64
- Insulin resistance with diabetes: Diabetologia 2014; 57(12): 2513-20
- Homocysteine level: J Am Geriatr Soc 2014; 62(2):213-21
- Subclinical thyroid dysfunction: Thyroid 2014; 24(2): 208-214
- Blood pressure: Am J Hypertens 2015; 28(4): 469-79
- Thrombin Generation: J Gerontol A 2015; 70(8): 982-8